Metformin+Pioglitazone+Sitagliptin is used in the treatment of Type 2 diabetes mellitus.
Metformin + Pioglitazone + Sitagliptin is a combination of three antidiabetic medications. Metformin decreases the amount of glucose you absorb from your food and the glucose made by the liver. It also increases the body’s response to insulin, a natural substance that controls the amount of glucose in the blood (blood sugar levels). Pioglitazone works by enhancing cellular responsiveness to insulin and increasing insulin-dependent glucose utilization and disposal. Sitagliptin helps to control blood sugar levels by increasing substances (incretins) in the body that make the pancreas release more insulin. It also signals the liver to stop producing sugar (glucose) when there is too much sugar in the blood.
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