Bosentan is used in the treatment of pulmonary arterial hypertension (PAH).
Bosentan is an endothelin receptor blocker. It blocks the action of endothelin (a natural substance) that causes blood vessels to narrow (constrict). This narrowing increases the pressure in the blood vessels of the lungs. Bosentan helps relax these blood vessels and increases the supply of blood to the lungs.
SIDE EFFECTS :
Respiratory tract infection, Headache, Flushing (sense of warmth in the face, ears, neck and trunk), Fluid retention.