Glibenclamide + Metformin + Pioglitazone belongs to the group of medications called ‘antidiabetic agents’ used in the treatment of Type 2 diabetes mellitus.
Glibenclamide , Metformin and Pioglitazone. They work by different mechanisms to provide better control of blood sugar when single or dual therapy is not effective. Glibenclamide is a sulfonylurea which works by increasing the amount of insulin released by the pancreas in order to lower the blood glucose. Metformin is a biguanide. It works by lowering glucose production in the liver, delaying glucose absorption from intestines and increasing the body’s sensitivity to insulin. Pioglitazone is a thiazolidinedione which further increases insulin sensitivity.
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